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以患者需求為核心,驅(qū)動(dòng)細(xì)胞免疫治療創(chuàng)新,實(shí)現(xiàn)癌癥可控化并最終治愈。

We strive to make patients-driven cellular immunotherapy innovation, to transform cancer into a manageable condition — and ultimately cure it.

2021
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Cancer Cell-Derived GABA Promotes β-Catenin-Mediated Tumor Growth and Immunosuppression.
Nat Cell Biol. Author manuscript; available in PMC: 2022 Aug 10.
Published in final edited form as: Nat Cell Biol. 2022 Feb 10;24(2):230–241. doi: 10.1038/s41556-021-00820-9
Huang D., Wang Y., Thompson J.W., Yin T., Alexander P.B., Qin D., Mudgal P., Wu H., Liang Y., Tan L., Pan C., Yuan L., Wan Y., Li Q.-J.,* and Wang X.F. (2021)

The lupus autoantigen La/Ssb is an Xist-binding protein involved in Xist folding and cloud formation.
Nucleic Acids Res. (20):11596-11613. (*: Corresponding authors, PMCID: PMC8599922)
Ha N., Ding N., Hong R., Liu R., Roca X., Luo Y., Duan X., Wang X., Ni P., Wu H., Zhang L.F.*, Chen L*. (2021) 

TIPS: trajectory inference of pathway significance through pseudotime comparison for functional assessment of single-cell RNAseq data.
Brief Bioinform. 22(5):bbab124. (*: Corresponding authors, PMCID: PMC8425418)
Zheng Z., Qiu X., Wu H., Chang L., Tang X., Zou L., Li J., Wu Y., Zhou J., Jiang S., Wan Y., Ni Q. (2021) 

 TCR repertoire characteristics predict clinical response to adoptive CTL therapy against nasopharyngeal carcinoma.
Oncoimmunology. 10(1):1955545. (*: Corresponding authors, PMCID: PMC8331028)
Wang G., Mudgal P., Wang L., Shuen T.W.H., Wu H., Alexander P.B., Wang W.W., Wan Y., Toh H.C.*, Wang X.-F.*, and Li Q.-J.* (2021)

Resident Memory T Cells in Tumor-Distant Tissues Fortify Against Metastasis Formation.
Cell Reports 35(6)109118 (PMCID: PMC8204287)
Christian L.S., Wang L., Wu H., Deng D., Lim B., Wang X.-F. and Li Q.-J. (2021)

Peripheral eosinophil counts predict efficacy of anti-CD19 CAR-T cell therapy against B-lineage non-Hodgkin lymphoma.
Theranostics 11(10):4699-4709. (*: Corresponding authors, PMCID: PMC7978305)
Jia Q., Qin D., He F., Xie Q., Ying Z., Zhang Y., Song Y., Cheng J.N., Zuo X., Xu L., Fang H., Hu C., Peng L., Jin T., Shi Z., Alexander P.B., Wang Y., Liu Y., Han W., Zhu J., Wang P.*, Li Q.-J.*, Zhu B.* (2021) 

Radiation-Induced Eosinophils Improve Cytotoxic T Lymphocyte Recruitment and Response to Immunotherapy.
Sci. Adv. 7(5):eabc7609. (*: Corresponding authors, PMCID: PMC7846170)
Cheng J.-N., Luo W., Sun C., Jin Z., Zeng X., Alexander P.B., Gong Z., Xia X., Ding X., Xu S., Zou P., Wan Y., Jia Q. *, Li Q.-J.*, & Zhu B. (2021)

The Landscape of Cell and Gene Therapies for Solid Tumors.
Cancer Cell. 39(1):7-8. (PMID: 33434513)
Wang S., Sun F., Huang H., Chen K., Li Q.J., Zhang L., Wang E., Wang C., Zhang H., Yuan A.Q., Chen B., Deng T., Liu Y., Sun J., Liu D., Yu Y., Fang Y., Jiang N., Wu D., Fang H., Bai Y., Xing S., Ni Y., Fan Q., Yu A., Sun C., Tang Y., Li N., Xu B., He J. (2021) 
03.23
2022
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